(to leave a place, especially because it is impossible or dangerous for you to stay):
The ship was sinking, and the captain gave the order to abandon ship.
desert (to leave a place, so that no one is left there): Due to bad weather, several villages had been deserted.
vacate (to leave a seat, room, or house so that it is available for other people):
You should vacate you room by noon on the day of departure.
evacuate (to leave a place because it is not safe): Residents have evacuated the area because of the fire.